Researcher
INSTITUTE OF MOLECULAR SCIENCES (IMS)
CENTRO DE QUÍMICA ESTRUTURAL (CQE) / Instituto Superior Técnico, Universidade de Lisboa
INSTITUTE OF MOLECULAR SCIENCES (IMS)
CENTRO DE QUÍMICA ESTRUTURAL (CQE) / Instituto Superior Técnico, Universidade de Lisboa
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- Luís Miguel Teodoro Frija was born in the picturesque village of Alenquer (Portugal), 1979
- Chemistry degree, University of Algarve, FCT-UAlg, 1997-2001
- Erasmus program grantee, Masarykova Univerzity, Czech Republic / University of Vienna, Austria, 2000
- Graduate research fellow, 2002-2004 (joint project, University of Algarve and University of Liverpool, UK)
- Ph.D., Chemistry - Organic Chemistry, University of Algarve, FCT-UAlg, 2004-2008 (work developed at M.L.S. Cristiano Lab., FCT-UAlg; and University of Coimbra, UC-DQ, R. Fausto Lab.)
- Founder and Scientific Director of TecnoCiLab, Lda. (Private laboratory, analytical chemistry & product development), 2008-present.
- Postdoctoral research fellow
- Faculty of Pharmacy - iMedULisboa, University of Lisbon, 2011-2014 (C.A.M Afonso Lab.)
- Instituto Superior Técnico, CQE, University of Lisbon, 2015-2018 (A. Pombeiro Lab.)
- Researcher at IMS / CQE, Instituto Superior Técnico, University of Lisbon, from 11/2018
As part of the COORDINATION CHEMISTRY AND CATALYSIS group at CQE (INSTITUTO SUPERIOR TÉCNICO) the research conducted by L. Frija is directed towards the discovery of new synthetic methodologies to produce pioneering MULTIFUNCTIONAL AZOLE-BASED CATALYSTS (e.g., molecules capable to change their functionality and/or stereoselectivity in situ via an external stimulus, such as UV or MW radiation) and LEADS FOR CANCER CHEMOTHERAPY (e.g. azole-based selective chelators in biological medium).
A significant expertise and effort on the development of new synthetic and catalytic methodologies has been maintained over the years in view of the fundamental challenges associated with selective handling of organic compounds possessing relevant pratical applications. Several of our molecules are often biologically active, displaying potential applicability in health care and plant protection. In addition, they often show complex molecular architectures and organic functionalities, which make them a challenge for total synthesis and a testing ground for novel methodologies.
Understanding the chemical reactivity, i.e., the tendency of a substance to undergo chemical changes in a system, is vital in our research and our reaction mechanisms explain how these changes occur... herein we talk about the heart of chemistry!
A significant expertise and effort on the development of new synthetic and catalytic methodologies has been maintained over the years in view of the fundamental challenges associated with selective handling of organic compounds possessing relevant pratical applications. Several of our molecules are often biologically active, displaying potential applicability in health care and plant protection. In addition, they often show complex molecular architectures and organic functionalities, which make them a challenge for total synthesis and a testing ground for novel methodologies.
Understanding the chemical reactivity, i.e., the tendency of a substance to undergo chemical changes in a system, is vital in our research and our reaction mechanisms explain how these changes occur... herein we talk about the heart of chemistry!
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Contacts Luís M. T. Frija Centro de Química Estrutural (CQE), Complexo I, Instituto Superior Técnico Universidade de Lisboa Av. Rovisco Pais, 1049-001 Lisbon, Portugal E-mail: luisfrija_at_tecnico.ulisboa.pt
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