International Peer-reviewed Articles
A35) Microwave-Assisted Oxidation of 1-Phenylethanol to Acetophenone Catalyzed by Cu(NO3)2∙2.5H2O under Solvent-Free Conditions
Luís M. T. Frija*, Bruno G. M. Rocha and Armando J. L. Pombeiro
J. Chem. Education, 2022 (in prep.)
A34) Rational design, synthesis and structure of copper and iron chelators active in cancer therapy – A revision on the most promising compounds
Luís M. T. Frija*, and Armando J. L. Pombeiro
Pharmaceuticals, 2022 (in prep.)
A33) Synthesis of non-symmetrical dispiro 1,2,4,5-tetraoxanes and 1,2,4-trioxanes catalyzed by Silica Sulfuric Acid
Patrícia S. M. Amado, Luís M. T. Frija, Jaime A. S. Coelho, Paul M. O’Neill*, and Maria L. S. Cristiano*
J. Org. Chem., 2021, 86, 10608-10620
A32) Solvent-free Oxidation of Benzyl Alcohols Catalysed by a Tetrazole-saccharinate Zn(II) Complex under Microwave Radiation: the role of the Ligand and the Reaction Mechanism
Luís M. T. Frija*, André L. Fernandes, M. Lurdes S. Cristiano and Armando J. L. Pombeiro
J. Mol. Struct., 2020, 1222, 128831 (pdf)
A31) Well-defined Nickel(II) Tetrazole-saccharinate Complex as Homogeneous Catalyst on the Reduction of Aldehydes: Scope and Reaction Mechanism
Luís M. T. Frija*, Bruno G. M. Rocha, Maxim L. Kuznetsov, Lília I. L. Cabral, M. Lurdes S. Cristiano and Armando J. L. Pombeiro
Pure & Applied Chemistry, 2020, 92, 151-166 (pdf)
A30) In vitro Assessment of Antimicrobial, Antioxidant and Cytotoxic Properties of Saccharin‑Tetrazolyl and ‑Thiadiazolyl Derivatives; The Simple Dependence of the pH Value on Antimicrobial Activity
Luís M. T. Frija*, Epole Ntungwe, Przemysław Sitarek, Joana M. Andrade, Monika Toma, Tomasz Śliwiński, Lília Cabral, M. Lurdes S. Cristiano, Patrícia Rijo* and Armando J. L. Pombeiro
Pharmaceuticals, 2019, 12, 167 (pdf)
A29) Synthesis, Structure and Cytotoxicity of a Novel Sulphanyl-Bridged Thiadiazolyl-Saccharinate Conjugate: The Relevance of S...N Interaction
L. Cabral, E. Brás, M. Henriques, C. Marques, L. M. T. Frija, L. Barreira, J. A. Paixão, R. Fausto*, M. L. S. Cristiano*
Chem. Eur. J., 2018, 24, 3251-3262 (pdf)
Anticancer Agents | Hot Paper
A28) Organocatalyzed oxidation of benzyl alcohols by a tetrazole-amino-saccharin: A combined experimental and theoretical (DFT) study
Luís M. T. Frija*, Maxim L. Kuznetsov, Bruno G.M. Rocha, Lília Cabral, M. Lurdes S. Cristiano, Maximilian N. Kopylovich, Armando J. L. Pombeiro
Molecular Catalysis, 2017, 442, 57-65 (pdf)
A27) Proteomic insights on the metabolism of Penicillium janczewskii during the biotransformation of the plant terpenoid labdanolic acid
Isabel Martins, Adélia Varela, Luís M. T. Frija, Mónica A. S. Estevão, Sébastien Planchon, Jenny Renaut, Carlos A. M. Afonso and Cristina S. Pereira*
Front. Bioeng. Biotechnol., 2017, 5:45, 1-12 (pdf)
A26) Building 1,2,4-Thiadiazole: Ten Years of Progress
Luís M. T. Frija*, Armando J. L. Pombeiro, Maximilian N. Kopylovich*
Eur. J. Org. Chem., 2017, 2670-2682 (pdf)
A25) Copper(II) and cobalt(II) tetrazole-saccharinate complexes as effective catalysts for oxidation of secondary alcohols
Luís M. T. Frija*, Elisabete C. B. A. Alegria, Manas Sutradhar, M. Lurdes S. Cristiano, Amin Ismael, Maximilian N. Kopylovich, Armando J. L. Pombeiro*
J. Mol. Catal. A: Chem., 2016, 425, 283-290 (pdf)
A24) Coordination Chemistry of Thiazoles, Isothiazoles and Thiadiazoles
Luís M. T. Frija*, Armando J. L. Pombeiro, Maximilian N. Kopylovich*
Coord. Chem. Rev., 2016, 308, 32-55 (pdf)
A23) Supported Acid-catalyzed Flash Vacuum Thermolysis on the Valorisation of Labdanum Resin
Luís M. T. Frija* and Carlos A. M. Afonso*
Biomass & Bioenergy, 2014, 71, 363-369 (pdf)
A22) Isolation, analytical quantification and seasonal variation of labdanolic acid from the Portuguese-grown Cistus ladaniferus
André N. C. Martins, Svilen P. Simeonov, Luís M. T. Frija*, Raquel Viveiros, Anita Lourenço, Mara S. da Silva, Teresa Casimiro, Carlos A. M. Afonso*
Ind. Crop. Prod., 2014, 60, 226-232 (pdf)
A21) Genesis of rare molecules using light-induced reactions of matrix-isolated tetrazoles
Luís M. T. Frija*, M. L. S. Cristiano, A. Gómez-Zavaglia, I. D. Reva, R. Fausto
J. Photochem. Photobiol. C: Photochem Rev., 2014, 18, 71-90 (http://dx.doi.org/10.1016/j.jphotochemrev.2013.09.001)
A20) Short Synthesis of the Natural Product 3beta-Hydroxy-labd-8 (17)-en-15-oic Acid via Microbial Transformation of Labdanolic Acid
Luís M. T. Frija*, Helga Garcia, Cátia Rodrigues, Isabel Martins, Nuno R. Candeias, Vânia André, M. Teresa Duarte, Cristina Silva Pereira* and Carlos A. M. Afonso*
Phytochem. Lett., 2013, 6, 165-169 (http://dx.doi.org/10.1016/j.phytol.2012.12.005)
A19) Amberlyst®-15: a Reusable Heterogeneous Catalyst for the Dehydration of Tertiary Alcohols
Luís M. T. Frija* and Carlos A. M. Afonso*
Tetrahedron, 2012, 68, 7414-7421 (http://dx.doi.org/10.1016/j.tet.2012.06.083)
A18) Sigmatropic Rearrangements in 5-Allyloxytetrazoles
Luís M. T. Frija, I. Reva, D. V. Coelho, A. Ismael, R. Fausto and M. L. S. Cristiano*
Org. Biomol. Chem., 2011, 9, 6040-6054 (http://dx.doi.org/10.1039/C1OB05460K)
A17) Isolation, Chemical and Bio-transformation Routes of Labdane-type Diterpenes
Luís M. T. Frija*, Raquel F. M. Frade* and Carlos A. M. Afonso*
Chemical Reviews, 2011, 111, 4418-4452 (http://dx.doi.org/10.1021/cr100258k)
A16) Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis
Luís M. T. Frija, Amin Ismael and M. L. S. Cristiano*
Molecules, 2010, 15, 3757-3774 (doi:10.3390/molecules15053757)
A15) Synthesis and Structure of Novel Benzisothiazole-tetrazolyl Derivatives for Potential Application as Nitrogen Ligands
Luís M. T. Frija, R. Fausto, Rui M. S. Loureiro and M. L. S. Cristiano*
J. Mol. Catal. A: Chem., 2009, 305, 142-146 (http://dx.doi.org/10.1016/j.molcata.2008.12.007)
A14) Photochemistry of Tetrazole Derivatives in Cryogenic Rare Gas Matrices
A. Gómez-Zavaglia, I. D. Reva, L. M. T. Frija, M. L. S. Cristiano and R. Fausto*
Chemical Physics Research Journal, 2009, Vol. 1, Issue 4, 221-250
(https://www.novapublishers.com/catalog/product_info.php?products_id=7195)
A13) Photochemistry of 5-Allyloxy-tetrazoles: Steady-state and Laser Flash-Photolysis Study
Luís M.T. Frija, I. V. Khmelinskii, I. D. Reva, C. Serpa, R. Fausto and M. L. S. Cristiano*
Org. Biomol. Chem., 2008, 6, 1046-1055 (http://dx.doi.org/10.1039/B718104C)
A12) UV-Induced Photochemistry of Matrix-Isolated 1-Phenyl-4-Allyl-Tetrazolone
Luís M. T. Frija, I. D. Reva, A. Gómez-Zavaglia, M. L. S. Cristiano and R. Fausto*
Photochem. Photobiol. Sci., 2007, 6, 1170-1176 (http://dx.doi.org/10.1039/B703961A)
A11) Photochemistry and Vibrational Spectra of Matrix-Isolated 5-Ethoxy-1-Phenyl-1H-Tetrazole
Luís M. T. Frija, I. D. Reva, A. Gómez-Zavaglia, M. L. S. Cristiano and R. Fausto
J. Phys. Chem. A., 2007, 111, 2879-2888 (http://dx.doi.org/10.1021/jp068556h)
A10) Photochemical Ring-opening and Intramolecular Hydrogen Shift Reactions in Sulfur Analogues of α-Pyrone
S. Breda, I. Reva, L. Lapinski, M. L. Cristiano, L. Frija and R. Fausto*
J. Phys. Chem. A., 2006, 110, 6415-6425 (http://dx.doi.org/10.1021/jp035155i)
A9) Infrared Spectrum and UV-Induced Photochemistry of 5-Methoxy-1-Phenyl-Tetrazole Isolated in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Photochem. Photobiol. A: Chem., 2006, 180, 175-183 (http://dx.doi.org/10.1016/j.jphotochem.2005.10.012)
A8) Molecular Structure, Vibrational Spectra and Photochemistry of 5-Mercapto-1-Methyltetrazole in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Mol. Struct., 2006, 786, 182-192 (http://dx.doi.org/10.1016/j.molstruc.2005.08.019)
A7) Mechanistic Investigations into the Photochemistry of 4-Allyl-tetrazolones in Solution; A New Approach to the Synthesis of 3,4-Dihydro-pyrimidinones
Luís M. T. Frija, Igor V. Khmelinskii and M. Lurdes S. Cristiano*
J. Org. Chem., 2006, 71, 3583-3591 (http://dx.doi.org/10.1021/jo060164j)
A6) Photochemistry of 1-Phenyl-Tetrazolone Isolated in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Photochem. Photobiol. A: Chem., 2006, 179, 243-255 (http://dx.doi.org/10.1016/j.jphotochem.2005.08.021)
A5) Palladium-catalysed Reduction of Heteroaromatic Naphthyl Ethers: Structural Effects on Reactivity
Luís M. T. Frija, M. Lurdes S. Cristiano*, Emanuel M. O. Guimarães, Nélson C. Martins and Jamie F. Bickley
J. Mol. Catal. A: Chem., 2005, 242, 241-250 (http://dx.doi.org/10.1016/j.molcata.2005.08.022)
A4) Novel Efficient Synthesis of 3,4-Dihydro-6-substituted-3-phenylpyrimidin-2(1H)-ones
Luís M. T. Frija, Igor V. Khmelinskii and M. Lurdes S. Cristiano*
Tetrahedron Lett., 2005, 46, 6757-6760 (http://dx.doi.org/10.1016/j.tetlet.2005.07.101)
A3) Molecular Structure, Vibrational Spectra and Photochemistry of 2-Methyl-2H-Tetrazol-5-Amine in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Phys. Chem. A., 2005, 109, 7967-7976 (http://dx.doi.org/10.1021/jp0517706)
A2) Heteroaromatic Benzyl Ethers as Intermediates for Heterogeneous Catalytic Transfer Hydrogenolysis of Benzyl Alcohols
Nuna C. P. Araújo, Amadeu F. Brigas*, M. Lurdes S. Cristiano*, Luís M. T. Frija, Emanuel M. O. Guimarães and Rui M. S. Loureiro
J. Mol. Catal. A: Chem., 2004, 215, 113-120 (http://dx.doi.org/10.1016/j.molcata.2003.12.033)
A1) Vibrational Spectra and Structure of 1-Phenyltetrazole and 5-Chloro-1-Phenyltetrazole. A Combined Study by Low Temperature Matrix Isolation and Solid State FTIR Spectroscopy and DFT Calculations
Susana C. S. Bugalho, Leszek Lapinski, M. Lurdes S. Cristiano, Luís M. T. Frija and Rui Fausto*
Vib. Spectrosc., 2002, 30, 213-225 (http://dx.doi.org/10.1016/S0924-2031(02)00028-0)
Book Chapters
BC5) Patrícia S. M. Amado, Luís M. T. Frija, Paul M. O’Neill and Maria L. S. Cristiano*; Synthesis of non-symmetrical 1,2,4,5-tetraoxanes: Past and current routes. In Synthesis and Applications in Chemistry and Materials, Edited by A. J. L. Pombeiro. World Scientific, 2022, in press.
BC4) Luís M. T. Frija*, André L. Fernandes, Bruno Guerreiro and M. Lurdes S. Cristiano; 1,2-Benzisothiazole 1,1-Dioxide (Saccharinate)-Based Compounds: Synthesis, Reactivity and Applications. In More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, Volume 3, Edited by Ana M. Phillips. United Kingdom: Wiley, 2022, in press.
BC3) Dmytro S. Nesterov*, Luís M. T. Frija*, Armando J. L. Pombeiro* and Maximilian N. Kopylovich*; Catalytic Alkane Amidation and Related Reactions, In Alkane Functionalization, First Edition. Chapter 19, pp. 427-448. Eds. A. J. L. Pombeiro and M. F. C. Guedes da Silva, Published 2019 by John Wiley & Sons Ltd. (pdf)
BC2) Carlos A. M. Afonso* and Luís M. T. Frija*; Isolamento e manipulação de um diterpeno da Flora Portuguesa, Exp. Nº7, In 100 Experiências de Química Orgânica, IST Press, 2011, pp. 25-28. ISBN: 978-989-8481-09-2. (http://istpress.tecnico.ulisboa.pt/node/344)
BC1) A. Gómez-Zavaglia, I. D. Reva, L. M. T. Frija, M. L. S. Cristiano and R. Fausto*; Photochemistry of Tetrazole Derivatives in Cryogenic Rare Gas Matrices, In Photochemistry Research Progress, 2008, Chapter 9, pp. 295-324. ISBN: 978-1-60456-568-3. Editors: Alejandro Sánchez and Sergio J. Gutierrez. Nova Science Publishers, Inc., NY, USA. (https://www.novapublishers.com/catalog/product_info.php?products_id=7189)
Theses
T2) Luís Miguel Teodoro Frija, PhD Thesis, Chemistry – Organic Chemistry; Title: Investigation of Structural Effects on the Reactivity of Heterocyclic Bioactive Compounds; University of Algarve, 27-10-2008, 10 copies.
T1) Luís Miguel Teodoro Frija, Scientific Project Thesis, Degree in Chemistry; Title: Design e Síntese de Compostos com Potencial Actividade Biológica; University of Algarve, 13-12-2001, 5 copies.
A35) Microwave-Assisted Oxidation of 1-Phenylethanol to Acetophenone Catalyzed by Cu(NO3)2∙2.5H2O under Solvent-Free Conditions
Luís M. T. Frija*, Bruno G. M. Rocha and Armando J. L. Pombeiro
J. Chem. Education, 2022 (in prep.)
A34) Rational design, synthesis and structure of copper and iron chelators active in cancer therapy – A revision on the most promising compounds
Luís M. T. Frija*, and Armando J. L. Pombeiro
Pharmaceuticals, 2022 (in prep.)
A33) Synthesis of non-symmetrical dispiro 1,2,4,5-tetraoxanes and 1,2,4-trioxanes catalyzed by Silica Sulfuric Acid
Patrícia S. M. Amado, Luís M. T. Frija, Jaime A. S. Coelho, Paul M. O’Neill*, and Maria L. S. Cristiano*
J. Org. Chem., 2021, 86, 10608-10620
A32) Solvent-free Oxidation of Benzyl Alcohols Catalysed by a Tetrazole-saccharinate Zn(II) Complex under Microwave Radiation: the role of the Ligand and the Reaction Mechanism
Luís M. T. Frija*, André L. Fernandes, M. Lurdes S. Cristiano and Armando J. L. Pombeiro
J. Mol. Struct., 2020, 1222, 128831 (pdf)
A31) Well-defined Nickel(II) Tetrazole-saccharinate Complex as Homogeneous Catalyst on the Reduction of Aldehydes: Scope and Reaction Mechanism
Luís M. T. Frija*, Bruno G. M. Rocha, Maxim L. Kuznetsov, Lília I. L. Cabral, M. Lurdes S. Cristiano and Armando J. L. Pombeiro
Pure & Applied Chemistry, 2020, 92, 151-166 (pdf)
A30) In vitro Assessment of Antimicrobial, Antioxidant and Cytotoxic Properties of Saccharin‑Tetrazolyl and ‑Thiadiazolyl Derivatives; The Simple Dependence of the pH Value on Antimicrobial Activity
Luís M. T. Frija*, Epole Ntungwe, Przemysław Sitarek, Joana M. Andrade, Monika Toma, Tomasz Śliwiński, Lília Cabral, M. Lurdes S. Cristiano, Patrícia Rijo* and Armando J. L. Pombeiro
Pharmaceuticals, 2019, 12, 167 (pdf)
A29) Synthesis, Structure and Cytotoxicity of a Novel Sulphanyl-Bridged Thiadiazolyl-Saccharinate Conjugate: The Relevance of S...N Interaction
L. Cabral, E. Brás, M. Henriques, C. Marques, L. M. T. Frija, L. Barreira, J. A. Paixão, R. Fausto*, M. L. S. Cristiano*
Chem. Eur. J., 2018, 24, 3251-3262 (pdf)
Anticancer Agents | Hot Paper
A28) Organocatalyzed oxidation of benzyl alcohols by a tetrazole-amino-saccharin: A combined experimental and theoretical (DFT) study
Luís M. T. Frija*, Maxim L. Kuznetsov, Bruno G.M. Rocha, Lília Cabral, M. Lurdes S. Cristiano, Maximilian N. Kopylovich, Armando J. L. Pombeiro
Molecular Catalysis, 2017, 442, 57-65 (pdf)
A27) Proteomic insights on the metabolism of Penicillium janczewskii during the biotransformation of the plant terpenoid labdanolic acid
Isabel Martins, Adélia Varela, Luís M. T. Frija, Mónica A. S. Estevão, Sébastien Planchon, Jenny Renaut, Carlos A. M. Afonso and Cristina S. Pereira*
Front. Bioeng. Biotechnol., 2017, 5:45, 1-12 (pdf)
A26) Building 1,2,4-Thiadiazole: Ten Years of Progress
Luís M. T. Frija*, Armando J. L. Pombeiro, Maximilian N. Kopylovich*
Eur. J. Org. Chem., 2017, 2670-2682 (pdf)
A25) Copper(II) and cobalt(II) tetrazole-saccharinate complexes as effective catalysts for oxidation of secondary alcohols
Luís M. T. Frija*, Elisabete C. B. A. Alegria, Manas Sutradhar, M. Lurdes S. Cristiano, Amin Ismael, Maximilian N. Kopylovich, Armando J. L. Pombeiro*
J. Mol. Catal. A: Chem., 2016, 425, 283-290 (pdf)
A24) Coordination Chemistry of Thiazoles, Isothiazoles and Thiadiazoles
Luís M. T. Frija*, Armando J. L. Pombeiro, Maximilian N. Kopylovich*
Coord. Chem. Rev., 2016, 308, 32-55 (pdf)
A23) Supported Acid-catalyzed Flash Vacuum Thermolysis on the Valorisation of Labdanum Resin
Luís M. T. Frija* and Carlos A. M. Afonso*
Biomass & Bioenergy, 2014, 71, 363-369 (pdf)
A22) Isolation, analytical quantification and seasonal variation of labdanolic acid from the Portuguese-grown Cistus ladaniferus
André N. C. Martins, Svilen P. Simeonov, Luís M. T. Frija*, Raquel Viveiros, Anita Lourenço, Mara S. da Silva, Teresa Casimiro, Carlos A. M. Afonso*
Ind. Crop. Prod., 2014, 60, 226-232 (pdf)
A21) Genesis of rare molecules using light-induced reactions of matrix-isolated tetrazoles
Luís M. T. Frija*, M. L. S. Cristiano, A. Gómez-Zavaglia, I. D. Reva, R. Fausto
J. Photochem. Photobiol. C: Photochem Rev., 2014, 18, 71-90 (http://dx.doi.org/10.1016/j.jphotochemrev.2013.09.001)
A20) Short Synthesis of the Natural Product 3beta-Hydroxy-labd-8 (17)-en-15-oic Acid via Microbial Transformation of Labdanolic Acid
Luís M. T. Frija*, Helga Garcia, Cátia Rodrigues, Isabel Martins, Nuno R. Candeias, Vânia André, M. Teresa Duarte, Cristina Silva Pereira* and Carlos A. M. Afonso*
Phytochem. Lett., 2013, 6, 165-169 (http://dx.doi.org/10.1016/j.phytol.2012.12.005)
A19) Amberlyst®-15: a Reusable Heterogeneous Catalyst for the Dehydration of Tertiary Alcohols
Luís M. T. Frija* and Carlos A. M. Afonso*
Tetrahedron, 2012, 68, 7414-7421 (http://dx.doi.org/10.1016/j.tet.2012.06.083)
A18) Sigmatropic Rearrangements in 5-Allyloxytetrazoles
Luís M. T. Frija, I. Reva, D. V. Coelho, A. Ismael, R. Fausto and M. L. S. Cristiano*
Org. Biomol. Chem., 2011, 9, 6040-6054 (http://dx.doi.org/10.1039/C1OB05460K)
A17) Isolation, Chemical and Bio-transformation Routes of Labdane-type Diterpenes
Luís M. T. Frija*, Raquel F. M. Frade* and Carlos A. M. Afonso*
Chemical Reviews, 2011, 111, 4418-4452 (http://dx.doi.org/10.1021/cr100258k)
A16) Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis
Luís M. T. Frija, Amin Ismael and M. L. S. Cristiano*
Molecules, 2010, 15, 3757-3774 (doi:10.3390/molecules15053757)
A15) Synthesis and Structure of Novel Benzisothiazole-tetrazolyl Derivatives for Potential Application as Nitrogen Ligands
Luís M. T. Frija, R. Fausto, Rui M. S. Loureiro and M. L. S. Cristiano*
J. Mol. Catal. A: Chem., 2009, 305, 142-146 (http://dx.doi.org/10.1016/j.molcata.2008.12.007)
A14) Photochemistry of Tetrazole Derivatives in Cryogenic Rare Gas Matrices
A. Gómez-Zavaglia, I. D. Reva, L. M. T. Frija, M. L. S. Cristiano and R. Fausto*
Chemical Physics Research Journal, 2009, Vol. 1, Issue 4, 221-250
(https://www.novapublishers.com/catalog/product_info.php?products_id=7195)
A13) Photochemistry of 5-Allyloxy-tetrazoles: Steady-state and Laser Flash-Photolysis Study
Luís M.T. Frija, I. V. Khmelinskii, I. D. Reva, C. Serpa, R. Fausto and M. L. S. Cristiano*
Org. Biomol. Chem., 2008, 6, 1046-1055 (http://dx.doi.org/10.1039/B718104C)
A12) UV-Induced Photochemistry of Matrix-Isolated 1-Phenyl-4-Allyl-Tetrazolone
Luís M. T. Frija, I. D. Reva, A. Gómez-Zavaglia, M. L. S. Cristiano and R. Fausto*
Photochem. Photobiol. Sci., 2007, 6, 1170-1176 (http://dx.doi.org/10.1039/B703961A)
A11) Photochemistry and Vibrational Spectra of Matrix-Isolated 5-Ethoxy-1-Phenyl-1H-Tetrazole
Luís M. T. Frija, I. D. Reva, A. Gómez-Zavaglia, M. L. S. Cristiano and R. Fausto
J. Phys. Chem. A., 2007, 111, 2879-2888 (http://dx.doi.org/10.1021/jp068556h)
A10) Photochemical Ring-opening and Intramolecular Hydrogen Shift Reactions in Sulfur Analogues of α-Pyrone
S. Breda, I. Reva, L. Lapinski, M. L. Cristiano, L. Frija and R. Fausto*
J. Phys. Chem. A., 2006, 110, 6415-6425 (http://dx.doi.org/10.1021/jp035155i)
A9) Infrared Spectrum and UV-Induced Photochemistry of 5-Methoxy-1-Phenyl-Tetrazole Isolated in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Photochem. Photobiol. A: Chem., 2006, 180, 175-183 (http://dx.doi.org/10.1016/j.jphotochem.2005.10.012)
A8) Molecular Structure, Vibrational Spectra and Photochemistry of 5-Mercapto-1-Methyltetrazole in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Mol. Struct., 2006, 786, 182-192 (http://dx.doi.org/10.1016/j.molstruc.2005.08.019)
A7) Mechanistic Investigations into the Photochemistry of 4-Allyl-tetrazolones in Solution; A New Approach to the Synthesis of 3,4-Dihydro-pyrimidinones
Luís M. T. Frija, Igor V. Khmelinskii and M. Lurdes S. Cristiano*
J. Org. Chem., 2006, 71, 3583-3591 (http://dx.doi.org/10.1021/jo060164j)
A6) Photochemistry of 1-Phenyl-Tetrazolone Isolated in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Photochem. Photobiol. A: Chem., 2006, 179, 243-255 (http://dx.doi.org/10.1016/j.jphotochem.2005.08.021)
A5) Palladium-catalysed Reduction of Heteroaromatic Naphthyl Ethers: Structural Effects on Reactivity
Luís M. T. Frija, M. Lurdes S. Cristiano*, Emanuel M. O. Guimarães, Nélson C. Martins and Jamie F. Bickley
J. Mol. Catal. A: Chem., 2005, 242, 241-250 (http://dx.doi.org/10.1016/j.molcata.2005.08.022)
A4) Novel Efficient Synthesis of 3,4-Dihydro-6-substituted-3-phenylpyrimidin-2(1H)-ones
Luís M. T. Frija, Igor V. Khmelinskii and M. Lurdes S. Cristiano*
Tetrahedron Lett., 2005, 46, 6757-6760 (http://dx.doi.org/10.1016/j.tetlet.2005.07.101)
A3) Molecular Structure, Vibrational Spectra and Photochemistry of 2-Methyl-2H-Tetrazol-5-Amine in Solid Argon
A. Gómez-Zavaglia, I. D. Reva, L. Frija, M. L. Cristiano and R. Fausto*
J. Phys. Chem. A., 2005, 109, 7967-7976 (http://dx.doi.org/10.1021/jp0517706)
A2) Heteroaromatic Benzyl Ethers as Intermediates for Heterogeneous Catalytic Transfer Hydrogenolysis of Benzyl Alcohols
Nuna C. P. Araújo, Amadeu F. Brigas*, M. Lurdes S. Cristiano*, Luís M. T. Frija, Emanuel M. O. Guimarães and Rui M. S. Loureiro
J. Mol. Catal. A: Chem., 2004, 215, 113-120 (http://dx.doi.org/10.1016/j.molcata.2003.12.033)
A1) Vibrational Spectra and Structure of 1-Phenyltetrazole and 5-Chloro-1-Phenyltetrazole. A Combined Study by Low Temperature Matrix Isolation and Solid State FTIR Spectroscopy and DFT Calculations
Susana C. S. Bugalho, Leszek Lapinski, M. Lurdes S. Cristiano, Luís M. T. Frija and Rui Fausto*
Vib. Spectrosc., 2002, 30, 213-225 (http://dx.doi.org/10.1016/S0924-2031(02)00028-0)
Book Chapters
BC5) Patrícia S. M. Amado, Luís M. T. Frija, Paul M. O’Neill and Maria L. S. Cristiano*; Synthesis of non-symmetrical 1,2,4,5-tetraoxanes: Past and current routes. In Synthesis and Applications in Chemistry and Materials, Edited by A. J. L. Pombeiro. World Scientific, 2022, in press.
BC4) Luís M. T. Frija*, André L. Fernandes, Bruno Guerreiro and M. Lurdes S. Cristiano; 1,2-Benzisothiazole 1,1-Dioxide (Saccharinate)-Based Compounds: Synthesis, Reactivity and Applications. In More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, Volume 3, Edited by Ana M. Phillips. United Kingdom: Wiley, 2022, in press.
BC3) Dmytro S. Nesterov*, Luís M. T. Frija*, Armando J. L. Pombeiro* and Maximilian N. Kopylovich*; Catalytic Alkane Amidation and Related Reactions, In Alkane Functionalization, First Edition. Chapter 19, pp. 427-448. Eds. A. J. L. Pombeiro and M. F. C. Guedes da Silva, Published 2019 by John Wiley & Sons Ltd. (pdf)
BC2) Carlos A. M. Afonso* and Luís M. T. Frija*; Isolamento e manipulação de um diterpeno da Flora Portuguesa, Exp. Nº7, In 100 Experiências de Química Orgânica, IST Press, 2011, pp. 25-28. ISBN: 978-989-8481-09-2. (http://istpress.tecnico.ulisboa.pt/node/344)
BC1) A. Gómez-Zavaglia, I. D. Reva, L. M. T. Frija, M. L. S. Cristiano and R. Fausto*; Photochemistry of Tetrazole Derivatives in Cryogenic Rare Gas Matrices, In Photochemistry Research Progress, 2008, Chapter 9, pp. 295-324. ISBN: 978-1-60456-568-3. Editors: Alejandro Sánchez and Sergio J. Gutierrez. Nova Science Publishers, Inc., NY, USA. (https://www.novapublishers.com/catalog/product_info.php?products_id=7189)
Theses
T2) Luís Miguel Teodoro Frija, PhD Thesis, Chemistry – Organic Chemistry; Title: Investigation of Structural Effects on the Reactivity of Heterocyclic Bioactive Compounds; University of Algarve, 27-10-2008, 10 copies.
T1) Luís Miguel Teodoro Frija, Scientific Project Thesis, Degree in Chemistry; Title: Design e Síntese de Compostos com Potencial Actividade Biológica; University of Algarve, 13-12-2001, 5 copies.
